IGHV4-39 Gene Summary [Human]

Predicted to enable antigen binding activity and immunoglobulin receptor binding activity. Predicted to be involved in several processes, including activation of immune response; defense response to other organism; and phagocytosis. Predicted to be located in extracellular region and plasma membrane. Predicted to be part of immunoglobulin complex, circulating. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Immunoglobulin Variable Gene
Official Symbol
IGHV4-39
Official Name
immunoglobulin heavy variable 4-39 [Source:HGNC Symbol;Acc:HGNC:5651]
Ensembl ID
ENSG00000211959
Bio databases IDs NCBI: 28394 Ensembl: ENSG00000211959
Aliases immunoglobulin heavy variable 4-39
Synonyms immunoglobulin heavy variable 4-39, VH
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human IGHV4-39 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Cdr3 domain

Pathways

Biological processes and signaling networks where the IGHV4-39 gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
regulated by
  • methylprednisolone

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • Plasma Membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human IGHV4-39 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • immune response
  • immunoglobulin mediated immune response

Cellular Component

Where in the cell the gene product is active
  • immunoglobulin complex
  • extracellular region
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • antigen binding

Gene-Specific Assays for Results You Can Trust

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