CSKMT Gene Summary [Human]
Enables protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine dimethylation; peptidyl-lysine monomethylation; and peptidyl-lysine trimethylation. Predicted to be located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | CSKMT |
| Official Name | citrate synthase lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:33113] |
| Ensembl ID | ENSG00000214756 |
| Bio databases IDs | |
| Aliases | citrate synthase lysine methyltransferase |
| Synonyms | citrate synthase lysine methyltransferase, METTL12, U99HG |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CSKMT often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- lysine N-methyltransferase
- protein-lysine N-methyltransferase
- enzyme
- protein binding
- methyltransferase domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CSKMT gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- peptidyl-lysine trimethylation
- peptidyl-lysine monomethylation
- protein methylation
- peptidyl-lysine dimethylation
Cellular Component
Where in the cell the gene product is active
- mitochondrion
Molecular Function
What the gene product does at the molecular level
- protein binding
- lysine N-methyltransferase activity
- protein-lysine N-methyltransferase activity