ACSM4 Gene Summary [Human]
Predicted to enable decanoate-CoA ligase activity and fatty-acyl-CoA synthase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid biosynthetic process. Predicted to be active in mitochondrial matrix. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ACSM4 |
| Official Name | acyl-CoA synthetase medium chain family member 4 [Source:HGNC Symbol;Acc:HGNC:32016] |
| Ensembl ID | ENSG00000215009 |
| Bio databases IDs | |
| Aliases | acyl-CoA synthetase medium chain family member 4, similar to olfactory specific medium-chain acyl CoA synthetase |
| Synonyms | acyl-CoA synthetase medium-chain family member 4, O-MACS |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ACSM4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- fatty-acid ligase
- AMP-binding enzyme
- acetate--CoA ligase
- benzoate-CoA ligase family
- CoA-ligase
- Adenylate forming domain, Class I superfamily
- enzyme
- amino acid adenylation domain
- AMP-binding enzyme C-terminal domain
- fatty-acyl-CoA synthase
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ACSM4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- acyl-CoA metabolic process
- fatty acid biosynthetic process
Cellular Component
Where in the cell the gene product is active
- mitochondrial matrix
Molecular Function
What the gene product does at the molecular level
- medium-chain fatty acid-CoA ligase activity
- ATP binding
- metal ion binding
- fatty-acyl-CoA synthase activity
- fatty acid ligase activity