TRGC2 Gene Summary [Human]
Predicted to be involved in adaptive immune response. Predicted to be integral component of membrane. Predicted to be part of T cell receptor complex. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | T-Cell Receptor Constant Gene |
| Official Symbol | TRGC2 |
| Official Name | T cell receptor gamma constant 2 [Source:HGNC Symbol;Acc:HGNC:12276] |
| Ensembl ID | ENSG00000227191 |
| Bio databases IDs | |
| Aliases | T cell receptor gamma constant 2, T-cell receptor, gamma, constant region C2 |
| Synonyms | T cell receptor gamma constant 2, T cell receptor γ constant 2, TCRGC2, TRGC2(2X), TRGC2(3X) |
| Species | Human, Homo sapiens |
Pathways
Biological processes and signaling networks where the TRGC2 gene in human plays a role, providing insight into its function and relevance in health or disease.
- Allograft Rejection Signaling
- Antiproliferative Role of TOB in T Cell Signaling
- Autoimmune Thyroid Disease Signaling
- Calcium-induced T Lymphocyte Apoptosis
- CCR5 Signaling in Macrophages
- Cdc42 Signaling
- CTLA4 Signaling in Cytotoxic T Lymphocytes
- Cytotoxic T Lymphocyte-mediated Apoptosis of Target Cells
- Dendritic Cell Maturation
- G Protein Signaling Mediated by Tubby
- Graft-versus-Host Disease Signaling
- IL-4 Signaling
- Lipid Antigen Presentation by CD1
- NF-κB Signaling
- Nur77 Signaling in T Lymphocytes
- OX40 Signaling Pathway
- PKCθ Signaling in T Lymphocytes
- SAPK/JNK Signaling
- T Cell Receptor Signaling
- TEC Kinase Signaling
- Th17 Activation Pathway
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- COVID-19
regulated by
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TRGC2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- immune response
- adaptive immune response
- T cell receptor signaling pathway
Cellular Component
Where in the cell the gene product is active
- external side of plasma membrane
- plasma membrane
- gamma-delta T cell receptor complex
Molecular Function
What the gene product does at the molecular level
- transmembrane signaling receptor activity