RPP21 Gene Summary [Human]

This locus represents naturally occurring read-through transcription between the neighboring TRIM39 (tripartite motif-containing 39) and RPP21 (ribonuclease P/MRP 21kDa subunit) genes on chromosome 6. The read-through transcript encodes a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Nov 2010]

Details

Type
Protein Coding
Official Symbol
RPP21
Official Name
ribonuclease P/MRP subunit p21 [Source:HGNC Symbol;Acc:HGNC:21300]
Ensembl ID
ENSG00000239865
Bio databases IDs NCBI: 79897 NCBI: 202658 Ensembl: ENSG00000239865
Aliases ribonuclease P/MRP subunit p21
Synonyms TRIM39R, TRIM39-RPP21 readthrough
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RPP21 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • coiled-coil (CC) domain of Drosophila brain tumor (brat) and similar proteins
  • B-Box C-terminal domain
  • zinc finger of C3HC4-type, RING
  • associated with SPRY domains
  • RNAse P Rpr2/Rpp21/SNM1 subunit domain
  • B-box-type zinc finger superfamily
  • RING-type zinc-finger
  • RING finger (Really Interesting New Gene) domain and U-box domain superfamily
  • Ring finger
  • B-box zinc finger
  • SPRY-associated domain
  • Zinc finger, C3HC4 type (RING finger)
  • zinc-RING finger domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • insomnia
  • neuroticism
  • herpes zoster

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.