PSG11 Gene Summary [Human]

The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy. PSGs comprise a subgroup of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily. For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009]

Details

Type
Protein Coding
Official Symbol
PSG11
Official Name
pregnancy specific beta-1-glycoprotein 11 [Source:HGNC Symbol;Acc:HGNC:9516]
Ensembl ID
ENSG00000243130
Bio databases IDs NCBI: 5680 Ensembl: ENSG00000243130
Aliases pregnancy specific beta-1-glycoprotein 11, pregnancy specific beta-1-glycoprotein 13
Synonyms pregnancy specific beta-1-glycoprotein 11, pregnancy specific β-1-glycoprotein 11, PSBG-11, PSBG-13, PSG13, PSG14
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PSG11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • immunoglobulin domain
  • Immunoglobulin like
  • RGD motif
  • Immunoglobulin I-set domain
  • protein binding
  • Immunoglobulin V-set domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • tetradecanoylphorbol acetate
  • CLDN7

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human PSG11 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • heterophilic cell-cell adhesion
  • female pregnancy

Cellular Component

Where in the cell the gene product is active
  • extracellular region
  • cell surface

Gene-Specific Assays for Results You Can Trust

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