CARD17 Gene Summary [Human]
Enables caspase binding activity and identical protein binding activity. Involved in cellular response to lipopolysaccharide and negative regulation of interleukin-1 beta production. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | CARD17 |
| Official Name | caspase recruitment domain family member 17 [Source:HGNC Symbol;Acc:HGNC:33827] |
| Ensembl ID | ENSG00000255221 |
| Bio databases IDs | |
| Aliases | caspase recruitment domain family member 17, caspase recruitment domain family member 17, pseudogene, Inhibitory CARD |
| Synonyms | CARD17, caspase recruitment domain family member 17, pseudogene, INCA, LOC105369467 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CARD17 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protease binding
- protein binding
- identical protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CARD17 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cellular response to lipopolysaccharide
- negative regulation of interleukin-1 beta production
- regulation of apoptotic process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- macromolecular complex
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- cysteine-type endopeptidase inhibitor activity