TCF24 Gene Summary [Human]

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in developmental process and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
TCF24
Official Name
transcription factor 24 [Source:HGNC Symbol;Acc:HGNC:32275]
Ensembl ID
ENSG00000261787
Bio databases IDs NCBI: 100129654 Ensembl: ENSG00000261787
Aliases transcription factor 24
Synonyms bHLHa25, Gm10567, Gm2330, LOC100045893, transcription factor 24
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TCF24 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • basic Helix Loop Helix (bHLH) domain superfamily
  • helix loop helix domain
  • protein binding
  • Helix-loop-helix DNA-binding domain

Pathways

Biological processes and signaling networks where the TCF24 gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • diabetic nephropathy
  • insulin-dependent diabetes mellitus
  • cerebral aneurysm
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human TCF24 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • developmental process
  • regulation of transcription from RNA polymerase II promoter

Cellular Component

Where in the cell the gene product is active
  • nucleus

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • RNA polymerase II regulatory region sequence-specific DNA binding
  • protein dimerization activity
  • sequence-specific DNA binding RNA polymerase II transcription factor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.