Adam21 Gene Summary [Mouse]

This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional metalloprotease enzyme. The encoded protein functions in the regulation of spermatogenesis in the testes and neurogenesis in the central nervous system. [provided by RefSeq, May 2016]

Details

Type
Protein Coding
Official Symbol
Adam21
Official Name
a disintegrin and metallopeptidase domain 21 [Source:MGI Symbol;Acc:MGI:1861229]
Ensembl ID
ENSMUSG00000008438
Bio databases IDs NCBI: 56622 Ensembl: ENSMUSG00000008438
Aliases a disintegrin and metallopeptidase domain 21
Synonyms Adam31, a disintegrin and metallopeptidase domain 21
Species
Mouse, Mus musculus

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Adam21 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Reprolysin family propeptide
  • ZnMc
  • ADAM cysteine-rich
  • Metallo-peptidase family M12B Reprolysin-like
  • Disintegrin
  • Reprolysin (M12B) family zinc metalloprotease

Pathways

Biological processes and signaling networks where the Adam21 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane
  • neurites
  • perikaryon
  • axons

Gene-Specific Assays for Results You Can Trust

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