Prss57 Gene Summary [Mouse]
Predicted to enable heparin binding activity and serine-type endopeptidase activity. Predicted to be involved in protein maturation and proteolysis. Predicted to be located in azurophil granule lumen. Predicted to be active in extracellular space. Orthologous to human PRSS57 (serine protease 57). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Prss57 |
| Official Name | protease, serine 57 [Source:MGI Symbol;Acc:MGI:1920356] |
| Ensembl ID | ENSMUSG00000020323 |
| Bio databases IDs | |
| Aliases | protease, serine 57 |
| Synonyms | 2900092M14Rik, Df2, GLGL782, NSP4, PRSSL1, serine protease 57, UNQ782 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Prss57 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Trypsin-like serine protease
- trypsin
- Tryp_SPc
- serine-type peptidase
- peptidase
- heparin binding
Pathways
Biological processes and signaling networks where the Prss57 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- azurophil granule lumen
- azurophil granules
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Prss57 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteolysis
Cellular Component
Where in the cell the gene product is active
- extracellular space
- azurophil granule lumen
Molecular Function
What the gene product does at the molecular level
- serine-type peptidase activity
- serine-type endopeptidase activity
- heparin binding