Eef2kmt Gene Summary [Mouse]
Predicted to enable protein-lysine N-methyltransferase activity. Predicted to be involved in peptidyl-lysine trimethylation. Predicted to be located in cytoplasm. Predicted to be part of protein-containing complex. Orthologous to several human genes including EEF2KMT (eukaryotic elongation factor 2 lysine methyltransferase). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Eef2kmt |
| Official Name | eukaryotic elongation factor 2 lysine methyltransferase [Source:MGI Symbol;Acc:MGI:1917761] |
| Ensembl ID | ENSMUSG00000022544 |
| Bio databases IDs | |
| Aliases | eukaryotic elongation factor 2 lysine methyltransferase |
| Synonyms | 5730409G15Rik, EFM3, eukaryotic elongation factor 2 lysine methyltransferase, Fam86, FAM86A, RGD1304969, SB153 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Eef2kmt often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein-lysine N-methyltransferase
- enzyme
- protein binding
- AdoMet_MTases
- methyltransferase domain
- Family of unknown function
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Eef2kmt gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- chromatin remodeling
- peptidyl-lysine trimethylation
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
- macromolecular complex
Molecular Function
What the gene product does at the molecular level
- protein binding
- histone methyltransferase activity
- protein-lysine N-methyltransferase activity