Cabp4 Gene Summary [Mouse]
Predicted to enable calcium channel regulator activity and transmembrane transporter binding activity. Acts upstream of or within neuron differentiation and phototransduction. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Is expressed in brain; eye; ganglia; lung; and male reproductive gland or organ. Orthologous to human CABP4 (calcium binding protein 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Cabp4 |
| Official Name | calcium binding protein 4 [Source:MGI Symbol;Acc:MGI:1920910] |
| Ensembl ID | ENSMUSG00000024842 |
| Bio databases IDs | |
| Aliases | calcium binding protein 4 |
| Synonyms | 2410038D05Rik, calcium binding protein 4 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cabp4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- EF-hand, calcium binding motif
- EF-hand domain
- EF-hand domain pair
- EF hand
- EF-hand, calcium binding motif, found in parvalbumin-like EF-hand family
- ion channel binding
- EFh
- EFh_PI-PLC
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
phenotypes
- abnormal brain morphology
- abnormal eye morphology
- abnormal heart morphology
- enlarged heart
- hydrocephaly
- increased prepulse inhibition
- abnormal cone electrophysiology
- abnormal eye electrophysiology
- abnormal eye physiology
- abnormal prepulse inhibition
- abnormal retina morphology
- abnormal retinal cone cell morphology
- abnormal retinal neuronal layer morphology
- abnormal retinal rod bipolar cell morphology
- abnormal retinal rod cell morphology
- abnormal retinal rod cell outer segment morphology
- abnormal rod electrophysiology
- decreased circulating insulin level
- thin retinal outer nuclear layer
- thin retinal outer plexiform layer
role in cell
- abnormal morphology
- morphogenesis
- differentiation
- electrophysiology
- development
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cytosol
- photoreceptor inner segments
- ribbon synapse