Cox8b Gene Summary [Mouse]
Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen. Located in mitochondrion. Part of respiratory chain complex IV. Is active in mitochondrial inner membrane. Is expressed in brown fat; heart; and tongue. Orthologous to human COX8BP (cytochrome c oxidase subunit 8B, pseudogene). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cox8b |
| Official Name | cytochrome c oxidase subunit 8B [Source:MGI Symbol;Acc:MGI:105958] |
| Ensembl ID | ENSMUSG00000025488 |
| Bio databases IDs | |
| Aliases | cytochrome c oxidase subunit 8B |
| Synonyms | CCO8A, Cox8h, COXVIII-H, Cytochrome c oxidase, cytochrome c oxidase subunit 8B, cytochrome c oxidase, subunit VIIIb |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cox8b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- cytochrome-c oxidase
- enzyme
- Cyt_c_Oxidase_VIII
Pathways
Biological processes and signaling networks where the Cox8b gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- mitochondrial inner membrane