Khdc4 Gene Summary [Mouse]

Enables RNA binding activity. Predicted to be involved in mRNA splice site recognition. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of spliceosomal complex. Predicted to be active in nucleus. Orthologous to human KHDC4 (KH domain containing 4, pre-mRNA splicing factor). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Khdc4
Official Name
KH domain containing 4, pre-mRNA splicing factor [Source:MGI Symbol;Acc:MGI:1921450]
Ensembl ID
ENSMUSG00000028060
Bio databases IDs NCBI: 74200 Ensembl: ENSMUSG00000028060
Aliases KH domain containing 4, pre-mRNA splicing factor
Synonyms 2810403A07Rik, A430106P18Rik, BLOM7, KH domain containing 4, pre-mRNA splicing factor, KIAA0907, RGD1565775, SNORA80EHG
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Khdc4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • K homology (KH) RNA-binding domain, type I
  • protein binding
  • RNA binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • breast carcinoma
  • peripheral arterial disease
role in cell
  • ferroptosis
  • cisplatin sensitivity

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Cytoplasm
  • spliceosomes
  • nuclear foci
  • nucleoplasm
  • nuclear speckles

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Khdc4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mRNA splice site selection

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • spliceosomal complex
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • RNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.