Nat8 Gene Summary [Mouse]
Predicted to enable L-cysteine-S-conjugate N-acetyltransferase activity and L-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor. Involved in gastrulation with mouth forming second. Predicted to be located in Golgi apparatus; endoplasmic reticulum membrane; and endoplasmic reticulum-Golgi intermediate compartment membrane. Orthologous to several human genes including NAT8 (N-acetyltransferase 8 (putative)). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Nat8 |
| Official Name | N-acetyltransferase 8 (GCN5-related) [Source:MGI Symbol;Acc:MGI:1915646] |
| Ensembl ID | ENSMUSG00000030004 |
| Bio databases IDs | |
| Aliases | N-acetyltransferase 8 (GCN5-related) |
| Synonyms | 0610037O16Rik, ATase2, CCNAT, Cml4, N-acetyltransferase 8, N-acetyltransferase 8 (GCN5-related) |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nat8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- cysteine-S-conjugate N-acetyltransferase
- Acetyltransferase (GNAT) family
- lysine N-acetyltransferase
- NAT_SF
- Acetyltransferase (GNAT) domain
- enzyme
- ribosomal-protein-alanine acetyltransferase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Golgi Apparatus
- Endoplasmic Reticulum
- ER-to-Golgi intermediate compartment
- endoplasmic reticulum membrane