Acsm2 Gene Summary [Mouse]

Predicted to enable benzoate-CoA ligase activity; fatty-acyl-CoA synthase activity; and medium-chain fatty acid-CoA ligase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid biosynthetic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; cranium; genitourinary system; and integumental system. Orthologous to several human genes including ACSM2B (acyl-CoA synthetase medium chain family member 2B). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Acsm2
Official Name
acyl-CoA synthetase medium-chain family member 2 [Source:MGI Symbol;Acc:MGI:2385289]
Ensembl ID
ENSMUSG00000030945
Bio databases IDs NCBI: 233799 Ensembl: ENSMUSG00000030945
Aliases acyl-CoA synthetase medium-chain family member 2
Synonyms acyl-CoA synthetase medium-chain family member 2, AI315615, MGC37245
Species
Mouse, Mus musculus

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Acsm2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • fatty-acid ligase
  • AMP-binding enzyme
  • benzoate-CoA ligase family
  • CoA-ligase
  • Adenylate forming domain, Class I superfamily
  • enzyme
  • benzoate-CoA ligase
  • amino acid adenylation domain
  • AMP-binding enzyme C-terminal domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • diabetes mellitus
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria

Gene-Specific Assays for Results You Can Trust

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