Itgb1bp2 Gene Summary [Mouse]
Enables calcium ion binding activity and zinc ion binding activity. Predicted to be involved in centrosome duplication. Located in Z disc. Is expressed in several structures, including diaphragm; limb mesenchyme; skeletal musculature; tarsus rest of mesenchyme; and tongue. Orthologous to human ITGB1BP2 (integrin subunit beta 1 binding protein 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Itgb1bp2 |
| Official Name | integrin beta 1 binding protein 2 [Source:MGI Symbol;Acc:MGI:1353420] |
| Ensembl ID | ENSMUSG00000031312 |
| Bio databases IDs | |
| Aliases | integrin beta 1 binding protein 2 |
| Synonyms | CHORDC3, integrin beta 1 binding protein 2, integrin subunit beta 1 binding protein 2, integrin subunit β 1 binding protein 2, integrin β 1 binding protein 2, ITGB1BP, MELUSIN, MSTP015, RGD1565015 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Itgb1bp2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CS domain
- zinc ion binding
- alpha-crystallin Hsps/p23-like
- integrin binding
- calcium ion binding
- tail domain
- CHORD
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Z line
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Itgb1bp2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- muscle organ development
- signal transduction
Cellular Component
Where in the cell the gene product is active
- Z disc
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- protein binding
- calcium ion binding
- integrin binding
- SH3 domain binding