Cd209d Gene Summary [Mouse]

Enables D-mannose binding activity and identical protein binding activity. Acts upstream of or within defense response to bacterium; endocytosis; and positive regulation of cytokine production. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in Coronavirus infectious disease (multiple); aspergillosis; dengue disease (multiple); human immunodeficiency virus infectious disease (multiple); and tuberculosis (multiple). Orthologous to human CLEC4M (C-type lectin domain family 4 member M) and CD209 (CD209 molecule). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cd209d
Official Name
CD209d antigen [Source:MGI Symbol;Acc:MGI:2157947]
Ensembl ID
ENSMUSG00000031495
Bio databases IDs NCBI: 170779 Ensembl: ENSMUSG00000031495
Aliases CD209d antigen
Synonyms Cd209, CD209d antigen, CD209d molecule, Clec4m, Dc-signr, mSIGNR3, RGD1561104, SIGN-R3
Species
Mouse, Mus musculus
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cd209d often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • viral receptor
  • C-type lectin (CTL)/C-type lectin-like (CTLD) domain
  • Lectin C-type domain
  • carbohydrate binding
  • identical protein binding
  • mannose binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
  • mannosylated lipoarabinomannan
disease
  • infection by bacteria
regulated by
regulates
  • TNF
  • cytokine
  • leukotriene B4
role in cell
  • proliferation
  • number
  • production in
  • abnormal morphology

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane
  • plasma membrane extracellular face

Gene-Specific Assays for Results You Can Trust

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