Cd209 Gene Summary [Rat]

Predicted to enable several functions, including D-mannose binding activity; identical protein binding activity; and virus receptor activity. Predicted to be involved in several processes, including B cell adhesion; positive regulation of T cell proliferation; and positive regulation of viral life cycle. Predicted to act upstream of or within several processes, including defense response to bacterium; positive regulation of cytokine production; and regulation of T cell proliferation. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in Coronavirus infectious disease; aspergillosis; dengue disease (multiple); human immunodeficiency virus infectious disease (multiple); and tuberculosis (multiple). Orthologous to human CD209 (CD209 molecule). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cd209
Official Name
CD209 molecule [Source:RGD Symbol;Acc:1561104]
Ensembl ID
ENSRNOG00000001017
Bio databases IDs NCBI: 363856 Ensembl: ENSRNOG00000001017
Aliases CD209 molecule
Synonyms Cd209, CD209d antigen, CD209d molecule, Clec4m, Dc-signr, mSIGNR3, RGD1561104, SIGN-R3
Species
Rat, Rattus norvegicus
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cd209 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • viral receptor
  • C-type lectin (CTL)/C-type lectin-like (CTLD) domain
  • Lectin C-type domain
  • carbohydrate binding
  • identical protein binding
  • mannose binding

Pathways

Biological processes and signaling networks where the Cd209 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
  • mannosylated lipoarabinomannan
disease
  • infection by bacteria
regulated by
regulates
  • TNF
  • cytokine
  • leukotriene B4
role in cell
  • proliferation
  • number
  • production in
  • abnormal morphology

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane
  • plasma membrane extracellular face

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