Lipi Gene Summary [Mouse]

Predicted to enable heparin binding activity and phospholipase activity. Predicted to be involved in lipid catabolic process. Predicted to be located in plasma membrane. Predicted to be active in extracellular space. Is expressed in mandible and maxilla. Orthologous to human LIPI (lipase I). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Lipi
Official Name
lipase, member I [Source:MGI Symbol;Acc:MGI:2443868]
Ensembl ID
ENSMUSG00000032948
Bio databases IDs NCBI: 320355 Ensembl: ENSMUSG00000032948
Aliases lipase, member I
Synonyms CT17, D930038D03Rik, lipase I, lipase, member I, LOC375108, lpd1, LPDL, mPA-PLA1 beta, mPA-PLA1 β, PLA1C, PRED5
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Lipi often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • alpha/beta hydrolases
  • lipase
  • enzyme
  • heparin binding
  • phospholipase

Pathways

Biological processes and signaling networks where the Lipi gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • COVID-19
  • Ewing sarcoma
  • osteosarcomagenesis
regulated by
regulates
  • phosphatidic acid
  • lipid

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • Plasma Membrane
  • membrane rafts

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Lipi gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • lipid catabolic process
  • phosphatidic acid biosynthetic process

Cellular Component

Where in the cell the gene product is active
  • extracellular space
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • heparin binding
  • carboxylic ester hydrolase activity
  • phospholipase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.