Nxnl1 Gene Summary [Mouse]
Predicted to enable receptor ligand activity. Involved in photoreceptor cell maintenance. Located in mitochondrion. Is expressed in several structures, including cerebellum external granule cell layer; neural retina; and olfactory epithelium. Orthologous to human NXNL1 (nucleoredoxin like 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Nxnl1 |
| Official Name | nucleoredoxin-like 1 [Source:MGI Symbol;Acc:MGI:1924446] |
| Ensembl ID | ENSMUSG00000034829 |
| Bio databases IDs | |
| Aliases | nucleoredoxin-like 1 |
| Synonyms | A930031O08Rik, LOC108353096, nucleoredoxin-like 1, RDCVF, TXNL6 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nxnl1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- thioredoxin-like domain
- Thioredoxin-like
- Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
- receptor agonist activity
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cone matrix sheath
- photoreceptor outer segments
- interphotoreceptor matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Nxnl1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- photoreceptor cell maintenance
Cellular Component
Where in the cell the gene product is active
- photoreceptor outer segment
Molecular Function
What the gene product does at the molecular level
- protein binding