Gjd4 Gene Summary [Mouse]

Predicted to enable gap junction channel activity. Acts upstream of or within regulation of satellite cell activation involved in skeletal muscle regeneration. Located in plasma membrane. Is expressed in several structures, including diaphragm; limb segment; liver; lung; and skeletal musculature. Orthologous to human GJD4 (gap junction protein delta 4). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Gjd4
Official Name
gap junction protein, delta 4 [Source:MGI Symbol;Acc:MGI:2444990]
Ensembl ID
ENSMUSG00000036855
Bio databases IDs NCBI: 225152 Ensembl: ENSMUSG00000036855
Aliases gap junction protein, delta 4
Synonyms 9430022F06Rik, Cx39, CX40.1, Cxnu, gap junction protein delta 4, gap junction protein, delta 4, gap junction protein δ 4, gap junction protein, δ 4
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gjd4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Connexin homologues
  • Gap junction channel protein cysteine-rich domain
  • transporter
  • Connexin

Pathways

Biological processes and signaling networks where the Gjd4 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Gjd4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • transmembrane transport
  • regulation of satellite cell activation involved in skeletal muscle regeneration
  • cell-cell signaling

Cellular Component

Where in the cell the gene product is active
  • connexon complex

Molecular Function

What the gene product does at the molecular level
  • gap junction channel activity