Hs3st6

Enables [heparan sulfate]-glucosamine 3-sulfotransferase activity. Involved in heparan sulfate proteoglycan biosynthetic process. Acts upstream of or within blastocyst hatching. Predicted to be located in Golgi membrane. Is expressed in several structures, including early conceptus; exocrine system; integumental system; lung; and nervous system. Human ortholog(s) of this gene implicated in hereditary angioedema. Orthologous to human HS3ST6 (heparan sulfate-glucosamine 3-sulfotransferase 6). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Hs3st6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Hs3st6 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Hs3st6 gene, providing context for its role in the cell.