Cbln3 Gene Summary [Mouse]

Predicted to be involved in maintenance of synapse structure. Located in extracellular space and synapse. Is active in parallel fiber to Purkinje cell synapse and synaptic cleft. Is expressed in several structures, including brain; genitourinary system; gut; respiratory system; and sensory organ. Orthologous to human CBLN3 (cerebellin 3 precursor). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cbln3
Official Name
cerebellin 3 precursor protein [Source:MGI Symbol;Acc:MGI:1889286]
Ensembl ID
ENSMUSG00000040380
Bio databases IDs NCBI: 56410 Ensembl: ENSMUSG00000040380
Aliases cerebellin 3 precursor protein
Synonyms cerebellin 3 precursor, cerebellin 3 precursor protein, PRO1486, RGD1563731
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cbln3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • C1q domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • gait disturbance
  • ataxia
  • motor dysfunction or movement disorder
regulated by
role in cell
  • innervation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • synapse
  • excitatory synapses

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Cbln3 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • extracellular space
  • endoplasmic reticulum
  • Golgi apparatus
  • synapse

Gene-Specific Assays for Results You Can Trust

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