Chil3 Gene Summary [Mouse]
The protein encoded by this gene is similar to bacterial chitinases but lacks chitinase activity. The encoded protein is thought to function as a lectin and may be involved in inflammation and allergy. [provided by RefSeq, Sep 2015]
Details
| Type | Protein Coding |
| Official Symbol | Chil3 |
| Official Name | chitinase-like 3 [Source:MGI Symbol;Acc:MGI:1330860] |
| Ensembl ID | ENSMUSG00000040809 |
| Bio databases IDs | |
| Aliases | chitinase-like 3 |
| Synonyms | Chi3l3, Chi3l4, Chil3, Chil4, Chitinase 3-like 3, Chitinase 3-like 4, chitinase-like 3, chitinase-like 4, ECF-L, rYM1olf, Ym1, Ym2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Chil3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- chitinase
- kinase binding
- Glycosyl hydrolases family 18
- GH18_chitinase-like
- beta-L-N-acetylhexosaminidase
- enzyme
- carbohydrate binding
- Glyco_18 domain
Pathways
Biological processes and signaling networks where the Chil3 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
- chitobiose
- chitotetrose
- chitotriose
- glucosamine
- D-galactosamine
- WDFY4
disease
- allergic pulmonary eosinophilia
- doxorubicin induced cardiotoxicity
role in cell
- chemotaxis
- activation
- proliferation
- quantity
- recruitment
- formation
- polarization
- extravasation
- response
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Extracellular Space
- granules
- cytoplasmic vesicles