Mill2 Gene Summary [Mouse]
Predicted to enable natural killer cell lectin-like receptor binding activity and receptor ligand activity. Predicted to be involved in immune response. Located in external side of plasma membrane. Orthologous to human MICA (MHC class I polypeptide-related sequence A) and MICB (MHC class I polypeptide-related sequence B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mill2 |
| Official Name | MHC I like leukocyte 2 [Source:MGI Symbol;Acc:MGI:2179989] |
| Ensembl ID | ENSMUSG00000040987 |
| Bio databases IDs | |
| Aliases | MHC I like leukocyte 2 |
| Synonyms | MHC class I polypeptide-related sequence B, MHC I like leukocyte 2, Micb |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mill2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Immunoglobulin C1-set domain
- Class I Histocompatibility antigen, domains alpha 1 and 2
- natural killer cell lectin-like receptor binding
- immunoglobulin domain
- receptor agonist activity
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- Extracellular Space
- plasma membrane extracellular face