Micb Gene Summary [Rat]

Predicted to enable natural killer cell lectin-like receptor binding activity. Predicted to be involved in several processes, including gamma-delta T cell activation; response to heat; and response to retinoic acid. Predicted to be active in external side of plasma membrane and extracellular space. Orthologous to human MICB (MHC class I polypeptide-related sequence B). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Micb
Official Name
MHC class I polypeptide-related sequence B [Source:RGD Symbol;Acc:1564508]
Ensembl ID
ENSRNOG00000057645
Bio databases IDs NCBI: 365212 Ensembl: ENSRNOG00000057645
Aliases MHC class I polypeptide-related sequence B
Synonyms MHC class I polypeptide-related sequence B, MHC I like leukocyte 2, Micb
Species
Rat, Rattus norvegicus
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Micb often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Immunoglobulin C1-set domain
  • Class I Histocompatibility antigen, domains alpha 1 and 2
  • natural killer cell lectin-like receptor binding
  • immunoglobulin domain
  • receptor agonist activity
  • protein binding

Pathways

Biological processes and signaling networks where the Micb gene in rat plays a role, providing insight into its function and relevance in health or disease.

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cell surface
  • Extracellular Space
  • plasma membrane extracellular face

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