Serpina5

Predicted to enable several functions, including enzyme binding activity; phosphatidylcholine binding activity; and retinoic acid binding activity. Involved in spermatogenesis. Predicted to be located in several cellular components, including external side of plasma membrane; extracellular exosome; and secretory granule. Predicted to be part of several cellular components, including protein C inhibitor-KLK3 complex; protein C inhibitor-PLAT complex; and protein C inhibitor-PLAU complex. Predicted to be active in extracellular space. Is expressed in several structures, including epithelium; genitourinary system; gut; musculoskeletal system; and skin. Orthologous to human SERPINA5 (serpin family A member 5). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Serpina5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Serpina5 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.