Ptchd4 Gene Summary [Mouse]

Predicted to be active in membrane. Is expressed in central nervous system; foot mesenchyme; and hindlimb interdigital region. Orthologous to human PTCHD4 (patched domain containing 4). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ptchd4
Official Name
patched domain containing 4 [Source:MGI Symbol;Acc:MGI:1920485]
Ensembl ID
ENSMUSG00000042256
Bio databases IDs NCBI: 627626 Ensembl: ENSMUSG00000042256
Aliases patched domain containing 4
Synonyms 3110082D06Rik, C6orf138, dJ402H5.2, FLJ41841, Gm321, patched domain containing 4, PTCH53, RGD1563020
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ptchd4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Patched family
  • Sterol-sensing domain of SREBP cleavage-activation

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
  • TP53
disease
  • colorectal cancer
  • COVID-19
  • tinnitus
  • gastroesophageal reflux
  • progression free survival
regulated by
regulates
role in cell
  • expression in
  • signaling in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ptchd4 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • membrane

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.