Serpinb9 Gene Summary [Mouse]
Enables serine-type endopeptidase inhibitor activity. Acts upstream of or within several processes, including T cell mediated cytotoxicity; acute inflammatory response to antigenic stimulus; and negative regulation of T cell apoptotic process. Located in cytoplasm. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human SERPINB9 (serpin family B member 9). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Serpinb9 |
| Official Name | serine (or cysteine) peptidase inhibitor, clade B, member 9 [Source:MGI Symbol;Acc:MGI:106603] |
| Ensembl ID | ENSMUSG00000045827 |
| Bio databases IDs | |
| Aliases | serine (or cysteine) peptidase inhibitor, clade B, member 9 |
| Synonyms | CAP-3, ovalbumin, PI-9, serine (or cysteine) peptidase inhibitor, clade B, member 9, Serine proteinase inhibitor mBM2A, serpin family B member 9, Spi6 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Serpinb9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protease binding
- SERine Proteinase INhibitors (serpin) family
- serine protease inhibitor activity
- caspase inhibitor activity
- protein binding
- Serpin (serine protease inhibitor)
Pathways
Biological processes and signaling networks where the Serpinb9 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- infection by RNA virus
regulates
- GZMB
- enzyme
role in cell
- apoptosis
- inhibition in
- development
- survival
- abnormal morphology
- cytotoxic reaction
- cytolysis by
- function
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Extracellular Space
- Nucleus
- Golgi Apparatus
- granules
- cytosol
- nucleoplasm