Zfp407 Gene Summary [Mouse]
Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in embryo; extraembryonic component; primitive endoderm; and yolk sac. Orthologous to human ZNF407 (zinc finger protein 407). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Zfp407 |
| Official Name | zinc finger protein 407 [Source:MGI Symbol;Acc:MGI:2685179] |
| Ensembl ID | ENSMUSG00000048410 |
| Bio databases IDs | |
| Aliases | zinc finger protein 407 |
| Synonyms | 6430585N13Rik, Gm333, Gm334, Gm948, RGD1310645, SIMHA, Zfp407, zinc finger protein 407 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Zfp407 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc finger, C2H2 type
- transcription regulator
- Zinc-finger double domain
- C2H2-type zinc-finger domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- insomnia
- colorectal cancer
- SIMHA syndrome
- alcoholism
- schizophrenia
- acute myeloid leukemia
- prostate cancer
regulates
- synthetic promoter
- DNA promoter
- SLC2A4
- 2-deoxyglucose
role in cell
- expression in
- transactivation in
- transcription in
- splicing in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Zfp407 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- DNA binding
- zinc ion binding