Krt71 Gene Summary [Mouse]
Predicted to be a structural constituent of skin epidermis. Involved in hair follicle morphogenesis. Located in keratin filament. Is expressed in eyelid epithelium; hair inner root sheath; lung; and vibrissa. Used to study hypotrichosis 13. Human ortholog(s) of this gene implicated in hypotrichosis 13. Orthologous to human KRT71 (keratin 71). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Krt71 |
| Official Name | keratin 71 [Source:MGI Symbol;Acc:MGI:1861586] |
| Ensembl ID | ENSMUSG00000051879 |
| Bio databases IDs | |
| Aliases | keratin 71 |
| Synonyms | Ca, Cal4, Cu, K6irs, K6irs1, keratin 71, Keratin complex 2, basic, gene 6g, Krt2-6g, Krt6g, mK6irs, mK6irs1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Krt71 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of cytoskeleton
- Intermediate filament protein
- Keratin type II head
Pathways
Biological processes and signaling networks where the Krt71 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intermediate filaments
- keratin intermediate filaments