Pmp2 Gene Summary [Mouse]
Predicted to enable cholesterol binding activity and fatty acid binding activity. Acts upstream of or within membrane organization. Predicted to be located in cytoplasm and myelin sheath. Predicted to be active in cytosol and nucleus. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 1G. Orthologous to human PMP2 (peripheral myelin protein 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pmp2 |
| Official Name | peripheral myelin protein 2 [Source:MGI Symbol;Acc:MGI:102667] |
| Ensembl ID | ENSMUSG00000052468 |
| Bio databases IDs | |
| Aliases | peripheral myelin protein 2 |
| Synonyms | P2, peripheral myelin protein 2 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pmp2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- cholesterol binding
- lipocalin/cytosolic fatty acid-binding protein family
- fatty acid binding
- Lipocalin / cytosolic fatty-acid binding protein family
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown