Fbxo6 Gene Summary [Mouse]
Enables carbohydrate binding activity. Contributes to ubiquitin protein ligase activity. Involved in ERAD pathway and SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Acts upstream of or within glycoprotein catabolic process. Located in endoplasmic reticulum quality control compartment. Part of SCF ubiquitin ligase complex. Is expressed in several structures, including genitourinary system; gut; hemolymphoid system gland; liver; and lung. Orthologous to human FBXO6 (F-box protein 6). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fbxo6 |
| Official Name | F-box protein 6 [Source:MGI Symbol;Acc:MGI:1354743] |
| Ensembl ID | ENSMUSG00000055401 |
| Bio databases IDs | |
| Aliases | F-box protein 6 |
| Synonyms | FBG2, F-box protein 6, Fbs2, Fbx6b, Fbxo6b |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fbxo6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- F-box domain
- F-box domain superfamily
- ubiquitin protein ligase activity
- F-box-like
- F-box associated region
- enzyme
- protein binding
- carbohydrate binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum