Kdm5d Gene Summary [Mouse]
Predicted to enable histone H3K4me/H3K4me2/H3K4me3 demethylase activity and nuclear androgen receptor binding activity. Acts upstream of or within T cell antigen processing and presentation. Predicted to be located in fibrillar center. Predicted to be active in chromatin and nucleus. Is expressed in several structures, including central nervous system; genitourinary system; heart; liver; and lung. Orthologous to human KDM5D (lysine demethylase 5D). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Kdm5d |
| Official Name | lysine (K)-specific demethylase 5D [Source:MGI Symbol;Acc:MGI:99780] |
| Ensembl ID | ENSMUSG00000056673 |
| Bio databases IDs | |
| Aliases | lysine (K)-specific demethylase 5D |
| Synonyms | H-Y, Jarid1d, lysine demethylase 5D, Smcy |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Kdm5d often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- C5HC2 zinc finger
- PHD zinc finger
- jmjN domain
- PLU-1-like protein
- RING finger (Really Interesting New Gene) domain and U-box domain superfamily
- androgen receptor binding
- PHD finger superfamily
- enzyme
- ARID/BRIGHT DNA binding domain
- RmlC-like cupin superfamily
- histone demethylase activity
- ARID/BRIGHT DNA binding domain family
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- fibrillar center