Rnase2b Gene Summary [Mouse]
Predicted to enable RNA nuclease activity and lipopolysaccharide binding activity. Predicted to be involved in chemotaxis; defense response to Gram-positive bacterium; and innate immune response in mucosa. Predicted to be active in extracellular space. Orthologous to human RNASE2 (ribonuclease A family member 2) and RNASE3 (ribonuclease A family member 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rnase2b |
| Official Name | ribonuclease, RNase A family, 2B (liver, eosinophil-derived neurotoxin) [Source:MGI Symbol;Acc:MGI:1858598] |
| Ensembl ID | ENSMUSG00000059606 |
| Bio databases IDs | |
| Aliases | ribonuclease, RNase A family, 2B (liver, eosinophil-derived neurotoxin) |
| Synonyms | Ear11, Ear5, mR5, Raf4, ribonuclease, RNase A family, 2A (liver, eosinophil-derived neurotoxin), ribonuclease, RNase A family, 2B (liver, eosinophil-derived neurotoxin), Rnase2a, Rnase2b |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rnase2b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ribonuclease
- enzyme
- RNase_A
- lipopolysaccharide binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space