Slc22a12 Gene Summary [Mouse]
Enables urate transmembrane transporter activity. Involved in urate transport. Located in brush border membrane. Is expressed in central nervous system; dorsal root ganglion; male reproductive gland or organ; metanephros; and retina layer. Orthologous to human SLC22A12 (solute carrier family 22 member 12). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Slc22a12 |
| Official Name | solute carrier family 22 (organic anion/cation transporter), member 12 [Source:MGI Symbol;Acc:MGI:1195269] |
| Ensembl ID | ENSMUSG00000061742 |
| Bio databases IDs | |
| Aliases | solute carrier family 22 (organic anion/cation transporter), member 12 |
| Synonyms | AI987855, OAT4L, Rst, Slc22al2, solute carrier family 22 (organic anion/cation transporter), member 12, URAT1 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slc22a12 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- benzoate transport
- Sugar (and other) transporter
- MFS transporter, sugar porter (SP) family
- Major Facilitator Superfamily
- Multidrug resistance protein
- phosphate:H+ symporter
- protein binding
- urate transporter
- cation transport protein
- transporter
- PDZ-domain binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- apical membrane
- brush border