Chia1 Gene Summary [Mouse]
Enables chitin binding activity and chitinase activity. Involved in chitin catabolic process. Located in cytoplasm. Is expressed in choroid plexus; lung; and nervous system. Human ortholog(s) of this gene implicated in asthma. Orthologous to human CHIA (chitinase acidic). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Chia1 |
| Official Name | chitinase, acidic 1 [Source:MGI Symbol;Acc:MGI:1932052] |
| Ensembl ID | ENSMUSG00000062778 |
| Bio databases IDs | |
| Aliases | chitinase, acidic 1 |
| Synonyms | 2200003E03Rik, AMCase, Chia, chitinase, acidic, chitinase, acidic 1, YNL |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Chia1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- chitinase
- kinase binding
- Glycosyl hydrolases family 18
- Chitin binding Peritrophin-A domain
- GH18_chitinase-like
- enzyme
- chitin binding
- Glyco_18 domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Cytoplasm