Mtx1 Gene Summary [Mouse]
Predicted to be involved in mitochondrion organization. Located in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; cerebral cortex ventricular layer; pharyngo-tympanic tube; skin; and submandibular gland primordium. Orthologous to human MTX1 (metaxin 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mtx1 |
| Official Name | metaxin 1 [Source:MGI Symbol;Acc:MGI:103025] |
| Ensembl ID | ENSMUSG00000064068 |
| Bio databases IDs | |
| Aliases | metaxin 1 |
| Synonyms | Gcap6, METAXIN 1, MTX, MTXN |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mtx1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Outer mitochondrial membrane transport complex protein
- Glutathione S-transferase, C-terminal domain
- C-terminal, alpha helical domain of the Glutathione S-transferase family
- Glutathione S-transferase N-terminal domain
- transmembrane domain
- Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
- protein binding
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Mitochondria
- mitochondrial outer membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mtx1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein import into mitochondrial outer membrane
- lactation
- inner mitochondrial membrane organization
- mitochondrion organization
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- membrane
- mitochondrial outer membrane
- mitochondrial sorting and assembly machinery complex
Molecular Function
What the gene product does at the molecular level
- protein binding