Amn1 Gene Summary [Mouse]
Predicted to enable cargo receptor activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and cobalamin transport. Is active in microvillus membrane. Orthologous to human AMN1 (antagonist of mitotic exit network 1 homolog). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Amn1 |
| Official Name | antagonist of mitotic exit network 1 [Source:MGI Symbol;Acc:MGI:2442933] |
| Ensembl ID | ENSMUSG00000068250 |
| Bio databases IDs | |
| Aliases | antagonist of mitotic exit network 1 |
| Synonyms | 5830467E07RIK, A230083D09, antagonist of mitotic exit network 1, antagonist of mitotic exit network 1 homolog, C730024G19Rik, LOC196394, RGD1308119 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Amn1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- cargo receptor activity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- microvilli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Amn1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Cellular Component
Where in the cell the gene product is active
- microvillus membrane
- SCF ubiquitin ligase complex