Zdhhc11 Gene Summary [Mouse]
Enables protein-cysteine S-palmitoyltransferase activity. Involved in antiviral innate immune response; peptidyl-L-cysteine S-palmitoylation; and positive regulation of defense response to virus by host. Located in endosome membrane. Is expressed in brain; male reproductive gland or organ; metanephros; and submandibular gland. Orthologous to human ZDHHC11 (zinc finger DHHC-type containing 11) and ZDHHC11B (zinc finger DHHC-type containing 11B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Zdhhc11 |
| Official Name | zinc finger, DHHC domain containing 11 [Source:MGI Symbol;Acc:MGI:1918414] |
| Ensembl ID | ENSMUSG00000069189 |
| Bio databases IDs | |
| Aliases | zinc finger, DHHC domain containing 11 |
| Synonyms | 4933421L13Rik, DHHC-11, Zdhhc20, zinc finger, DHHC domain containing 11, zinc finger, DHHC-type containing 11, Znf399 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Zdhhc11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding activity, bridging
- protein-cysteine S-palmitoleyltransferase
- DHHC palmitoyltransferase
- enzyme
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
role in cell
- loss in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum
- endosomal membrane