Wfdc8 Gene Summary [Mouse]
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region and membrane. Is expressed in epididymis and testis. Orthologous to human WFDC8 (WAP four-disulfide core domain 8). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Wfdc8 |
| Official Name | WAP four-disulfide core domain 8 [Source:MGI Symbol;Acc:MGI:2685552] |
| Ensembl ID | ENSMUSG00000070533 |
| Bio databases IDs | |
| Aliases | WAP four-disulfide core domain 8 |
| Synonyms | C20orf170, dJ461P17.1, Gm706, HEL-S-292, LOC499942, WAP8, WAP four-disulfide core domain 8, Wfdc8-ps1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Wfdc8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- WAP-type (Whey Acidic Protein) 'four-disulfide core'
- Kunitz/Bovine pancreatic trypsin inhibitor (BPTI) domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Wfdc8 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular region
Molecular Function
What the gene product does at the molecular level
- serine-type endopeptidase inhibitor activity