Details
| Type | Retained Intron |
| Official Symbol | C4b |
| Official Name | complement component 4B (Chido blood group) [Source:MGI Symbol;Acc:MGI:88228] |
| Ensembl ID | ENSMUSG00000073418 |
| Bio databases IDs | |
| Aliases | complement component 4B (Chido blood group) |
| Species | Mouse, Mus musculus |
Pathways
Biological processes and signaling networks where the C4b gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
phenotypes
- decreased circulating alkaline phosphatase level
- impaired glucose tolerance
- abnormal blood coagulation
- abnormal glucose tolerance
- abnormal humoral immune response
- abnormal immune system physiology
- abnormal intestine morphology
- abnormal renal glomerulus morphology
- abnormal spleen germinal center morphology
- decreased spleen germinal center number
- decreased spleen germinal center size
- decreased susceptibility to Coronaviridae infection
- decreased susceptibility to bacterial infection
- decreased vascular permeability
- glomerulonephritis
- increased anti-double stranded DNA antibody level
- increased anti-nuclear antigen antibody level
- increased anti-single stranded DNA antibody level
- increased macrophage cell number
- increased neutrophil cell number
- increased sensitivity to induced morbidity/mortality
- increased spleen germinal center number
- increased spleen weight
- increased susceptibility to bacterial infection induced morbidity/mortality
- liver inflammation
- renal glomerular protein deposits