Defb18 Gene Summary [Mouse]
Predicted to be involved in defense response to bacterium and innate immune response. Predicted to be located in extracellular region. Orthologous to human DEFB113 (defensin beta 113). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Defb18 |
| Official Name | defensin beta 18 [Source:MGI Symbol;Acc:MGI:3648148] |
| Ensembl ID | ENSMUSG00000073735 |
| Bio databases IDs | |
| Aliases | defensin beta 18 |
| Synonyms | BD-18, DEFB-13, Defb18, defensin beta 113, defensin beta 18, defensin β 113, defensin β 18, EG654460, mBD-18 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Defb18 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Beta defensin
Pathways
Biological processes and signaling networks where the Defb18 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Defb18 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- innate immune response
- defense response to bacterium
Cellular Component
Where in the cell the gene product is active
- extracellular region