Mef2b Gene Summary [Mouse]
This locus represents naturally occurring readthrough transcription between the neighboring 2310045N01Rik (RIKEN cDNA 2310045N01 gene) and Mef2b (myocyte enhancer factor 2B) genes on chromosome 8. The readthrough transcript encodes a protein that shares sequence identity with the downstream gene product. [provided by RefSeq, Jun 2015]
Details
| Type | Protein Coding |
| Official Symbol | Mef2b |
| Official Name | myocyte enhancer factor 2B [Source:MGI Symbol;Acc:MGI:104526] |
| Ensembl ID | ENSMUSG00000079033 |
| Bio databases IDs | |
| Aliases | myocyte enhancer factor 2B |
| Synonyms | 2310045n01rik-mef2b, Gm45929, myocyte enhancer factor 2B like |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mef2b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- MADS
- RNA polymerase II transcription regulatory region sequence-specific binding transcriptional activator activity
- transcription regulator
- SRF-type transcription factor (DNA-binding and dimerization domain)
- double-stranded DNA binding
- nucleic acid binding
- histone deacetylase binding
- sequence-specific DNA binding
Pathways
Biological processes and signaling networks where the Mef2b gene in mouse plays a role, providing insight into its function and relevance in health or disease.
- Apelin Endothelial Signaling Pathway
- Calcium Signaling
- Cardiac Hypertrophy Signaling
- Cholecystokinin/Gastrin-mediated Signaling
- Corticotropin Releasing Hormone Signaling
- ERK5 Signaling
- G-Protein Coupled Receptor Signaling
- Gα12/13 Signaling
- p38 MAPK Signaling
- Role of NFAT in Cardiac Hypertrophy
- Role of NFAT in Regulation of the Immune Response
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cell junction
- cytosol
- nucleoplasm