Alkbh1 Gene Summary [Mouse]
Enables broad specificity oxidative DNA demethylase activity and chemoattractant activity. Involved in positive regulation of gene expression, epigenetic and regulation of translational initiation by tRNA modification. Acts upstream of or within several processes, including generation of neurons; in utero embryonic development; and negative regulation of neuron apoptotic process. Located in euchromatin. Is expressed in several structures, including branchial arch; central nervous system; hemolymphoid system gland; hindlimb muscle; and limb bud. Orthologous to human ALKBH1 (alkB homolog 1, histone H2A dioxygenase). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Alkbh1 |
| Official Name | alkB homolog 1, histone H2A dioxygenase [Source:MGI Symbol;Acc:MGI:2384034] |
| Ensembl ID | ENSMUSG00000079036 |
| Bio databases IDs | |
| Aliases | alkB homolog 1, histone H2A dioxygenase |
| Synonyms | neural regeneration protein |
| Species | Mouse, Mus musculus |
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown