Dchs2 Gene Summary [Mouse]
Predicted to enable calcium ion binding activity. Acts upstream of or within condensed mesenchymal cell proliferation and nephron development. Predicted to be active in cell-cell junction. Is expressed in brain; pharyngo-tympanic tube; and spinal cord. Orthologous to human DCHS2 (dachsous cadherin-related 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dchs2 |
| Official Name | dachsous cadherin related 2 [Source:MGI Symbol;Acc:MGI:2685263] |
| Ensembl ID | ENSMUSG00000102692 |
| Bio databases IDs | |
| Aliases | dachsous cadherin related 2 |
| Synonyms | CDH27, CDHJ, CDHR7, dachsous cadherin-related 2, EG627094, Gm417, Gm6731, LOC100534287, PCDH23, PCDHJ, RGD1563329 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dchs2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Cadherin repeat-like domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Dchs2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nephron development
- homophilic cell adhesion
- condensed mesenchymal cell proliferation
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- calcium ion binding