Abhd8 Gene Summary [Rat]
Predicted to enable carboxylic ester hydrolase activity and lysophosphatidic acid acyltransferase activity. Predicted to be involved in lipid homeostasis and phosphatidic acid biosynthetic process. Predicted to be active in mitochondrion. Orthologous to human ABHD8 (abhydrolase domain containing 8). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Abhd8 |
| Official Name | abhydrolase domain containing 8 [Source:RGD Symbol;Acc:1305693] |
| Ensembl ID | ENSRNOG00000000054 |
| Bio databases IDs | |
| Aliases | abhydrolase domain containing 8 |
| Synonyms | 0910001L24RIK, abhydrolase domain containing 8 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Abhd8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- alpha/beta hydrolase fold
- alpha/beta hydrolases
- Alpha/beta hydrolase family
- Serine aminopeptidase, S33
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Abhd8 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
Molecular Function
What the gene product does at the molecular level
- protein binding
- hydrolase activity