ABHD8 Gene Summary [Human]
This gene is upstream of, and in a head-to-head orientation with the gene for the mitochondrial ribosomal protein L34. The predicted protein contains alpha/beta hydrolase fold and secretory lipase domains. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | ABHD8 |
| Official Name | abhydrolase domain containing 8 [Source:HGNC Symbol;Acc:HGNC:23759] |
| Ensembl ID | ENSG00000127220 |
| Bio databases IDs | |
| Aliases | abhydrolase domain containing 8 |
| Synonyms | 0910001L24RIK, abhydrolase domain containing 8 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ABHD8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- alpha/beta hydrolase fold
- alpha/beta hydrolases
- Alpha/beta hydrolase family
- Serine aminopeptidase, S33
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ABHD8 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
Molecular Function
What the gene product does at the molecular level
- protein binding
- hydrolase activity