Ccz1b Gene Summary [Rat]
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in vesicle-mediated transport. Predicted to be part of Mon1-Ccz1 complex. Predicted to be active in intracellular membrane-bounded organelle. Orthologous to several human genes including CCZ1 (CCZ1 homolog, vacuolar protein trafficking and biogenesis associated). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Ccz1b |
| Official Name | CCZ1 homolog B, vacuolar protein trafficking and biogenesis associated [Source:RGD Symbol;Acc:1306410] |
| Ensembl ID | ENSRNOG00000001032 |
| Bio databases IDs | |
| Aliases | CCZ1 homolog B, vacuolar protein trafficking and biogenesis associated |
| Synonyms | C7orf28A, CCZ1A, Ccz1b, CCZ1 homolog, vacuolar protein trafficking and biogenesis associated, CCZ1 vacuolar protein trafficking and biogenesis associated, CGI-43, H DJ1163J12.2, MGC56855, RGD1306410 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ccz1b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- guanyl-nucleotide exchange factor
- Intu longin-like domain 3
- protein binding
- Intu longin-like domain 2
- First Longin domain of INTU, CCZ1 and HPS4
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Ccz1b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- vesicle-mediated transport
Cellular Component
Where in the cell the gene product is active
- intracellular membrane-bounded organelle
- Mon1-Ccz1 complex
- cytosol
- lysosomal membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- guanyl-nucleotide exchange factor activity